Models of host-parasite interaction and MHC polymorphism.

Models of host-parasite interaction and MHC polymorphism.

Recognition and polymorphism in host-parasite genetics.

Genetic specificity occurs in many host-parasite systems. Each host can recognize and resist only a subset of parasites; each parasite can grow only on particular hosts. Biochemical recognition systems determine which matching host and parasite genotypes result in resistance or disease. Recognition systems are often associated with widespread genetic polymorphism in the host and parasite popula...

Polymorphism in multilocus host parasite coevolutionary interactions.

Numerous loci in host organisms are involved in parasite recognition, such as major histocompatibility complex (MHC) genes in vertebrates or genes involved in gene-for-gene (GFG) relationships in plants. Diversity is commonly observed at such loci and at corresponding loci encoding antigenic molecules in parasites. Multilocus theoretical models of host-parasite coevolution predict that polymorp...

Host-parasite models on graphs.

The behavior of two interacting populations "hosts" and "parasites" is investigated on Cayley trees and scale-free networks. In the former case analytical and numerical arguments elucidate a phase diagram for the susceptible-infected-susceptible model, whose most interesting feature is the absence of a tricritical point as a function of the two independent spreading parameters. For scale-free g...

Spatial heterogeneity and polymorphism in host - parasite interactions

Section 1. Direct frequency-dependent selection (on any gene) generated by migration between two demes with different environments is negatively correlated with allele frequency. Section 2. Direct frequency-dependent selection is also generated by migration between demes with different environments if migration takes place before selection. Section 3. Dependence of parasite equilibrium allele f...